MATCHSTAT

San Francisco 49ers vs Jacksonville Jaguars: Prediction, Head-to-Head, Odds & Stats (Sun, 28 Sep '25)

Wojtek Kolan

Wojtek Kolan

Published on 28 Sep, 08:05 PM UTC

Next Match 28/09/25 at 08:05 PM

San Francisco 49ers vs Jacksonville Jaguars
📍 Levi's Stadium, USA.

Scheduled H2H Match For San Francisco 49ers Vs Jacksonville Jaguars

NFL

Sun, 28 Sep 2025 at 08:05 PM UTC

San Francisco 49ers
San Francisco 49ers

USA USA

Recent Form

W
W
W
W
W
Jacksonville Jaguars
Jacksonville Jaguars

USA USA

Recent Form

W
L
W
L
D

3

Win

Played

3
0 Draws

0

Win

2
Position
14
Kyle Shanahan
Manager
Doug Pederson

Game Schedule - Time Of Fixture

San Francisco 49ers will square off vs Jacksonville Jaguars in NFL on Sun, 28 Sep 2025 at 08:05 PM UTC. Let’s investigate historical performances, recent stats and head-2-head information to find out the most accurate picks and best bets.

San Francisco 49ers vs Jacksonville Jaguars Pick

Calculated from the implicit expectation from the odds, San Francisco 49ers have a 63.69% to get the victory. {Subscribe to|Join} the Matchstat.com {predictions|picks} club to {compare|reveal|get data on|find out} implied {and|vs} {actual|our expert} predictions to discover {edge|value bets|today’s highly profitable bets} {in order to|so you can} {see the best bets|win big|make successful bets|unlock winning bets}.

PredictionChance to win
San Francisco 49ers63.69 %
Jacksonville Jaguars38.76 %

Above is calculated from odds. Login / Signup to find out our expert picks.

San Francisco 49ers vs Jacksonville Jaguars H2H Results Summary

Over the last 3 H2H games for these competitors, San Francisco 49ers have come out on top 3 times and Jacksonville Jaguars have come out on top on 0 occasion. In the most recent match between them, San Francisco 49ers won 3-34.


Head-to-HeadMatch Wins
San Francisco 49ers3
Jacksonville Jaguars0

San Francisco 49ers vs Jacksonville Jaguars Best Odds For The Match

Winner (incl. overtime)
1W
1.57
2W
2.58
Regular Time Result
1W
1.5900000333786
2W
2.55999994277954
X
15

San Francisco 49ers vs Jacksonville Jaguars Premium Model Predictions With Edge

NFL.
Jaguars vs. …
.28 Sept 25 at 08:05 PM
Jaguars win
Probability:
40.25%
Edge:
0.85%
Odds:
+154
NFL.
Jaguars vs. …
.28 Sept 25 at 08:05 PM
49ers -3.5
Probability:
50.25%
Edge:
-0.25%
Odds:
-102

This data is only Bookie Predictions.

Unlock all our Expert winning predictions by becoming a member.

GET AMERICAN FOOTBALL PRO
NFL.
Jaguars vs. …
.28 Sept 25 at 08:05 PM
Under 47
Probability:
Edge:
-0.05%
Odds:
View All NFL Predictions With Edge picks

San Francisco 49ers vs Jacksonville Jaguars Past H2H Matches

9464
NFL
06:00 PM
12/11/23
4386
Jacksonville Jaguars
3
4389
San Francisco 49ers
34
06:00 PM
21/11/21
4386
Jacksonville Jaguars
10
4389
San Francisco 49ers
30
09:05 PM
24/12/17
4389
San Francisco 49ers
44
4386
Jacksonville Jaguars
33

Head To Head Streaks

4389
Wins
3

Team Streaks

4389
Wins
5

San Francisco 49ers Recent Matches

9464
NFL (24 Matches)
08:25 PM
21/09/25
4389
San Francisco 49ers
16
4412
Arizona Cardinals
15
W
05:00 PM
14/09/25
4425
New Orleans Saints
21
4389
San Francisco 49ers
26
W
08:05 PM
07/09/25
4430
Seattle Seahawks
13
4389
San Francisco 49ers
17
W
09:25 PM
05/01/25
4412
Arizona Cardinals
47
4389
San Francisco 49ers
24
L
01:15 AM
31/12/24
4389
San Francisco 49ers
34
4419
Detroit Lions
40
L
09:25 PM
22/12/24
4287
Miami Dolphins
29
4389
San Francisco 49ers
17
L
01:15 AM
13/12/24
4389
San Francisco 49ers
6
4387
Los Angeles Rams
12
L
09:25 PM
08/12/24
4389
San Francisco 49ers
38
4391
Chicago Bears
13
W
01:20 AM
02/12/24
4414
Buffalo Bills
35
4389
San Francisco 49ers
10
L
09:25 PM
24/11/24
4420
Green Bay Packers
38
4389
San Francisco 49ers
10
L
09:05 PM
17/11/24
4389
San Francisco 49ers
17
4430
Seattle Seahawks
20
L
06:00 PM
10/11/24
4388
Tampa Bay Buccaneers
20
4389
San Francisco 49ers
23
W
12:20 AM
28/10/24
4389
San Francisco 49ers
30
4392
Dallas Cowboys
24
W
08:25 PM
20/10/24
4389
San Francisco 49ers
18
4422
Kansas City Chiefs
28
L
12:15 AM
11/10/24
4430
Seattle Seahawks
24
4389
San Francisco 49ers
36
W
08:05 PM
06/10/24
4389
San Francisco 49ers
23
4412
Arizona Cardinals
24
L
08:05 PM
29/09/24
4389
San Francisco 49ers
30
4424
New England Patriots
13
W
08:25 PM
22/09/24
4387
Los Angeles Rams
27
4389
San Francisco 49ers
24
L
05:00 PM
15/09/24
4423
Minnesota Vikings
23
4389
San Francisco 49ers
17
L
12:15 AM
10/09/24
4389
San Francisco 49ers
32
4427
New York Jets
19
W
11:30 PM
11/02/24
4422
Kansas City Chiefs
25
4389
San Francisco 49ers
22
L
11:30 PM
28/01/24
4389
San Francisco 49ers
34
4419
Detroit Lions
31
W
01:15 AM
21/01/24
4389
San Francisco 49ers
24
4420
Green Bay Packers
21
W
09:25 PM
07/01/24
4389
San Francisco 49ers
20
4387
Los Angeles Rams
21
L
9465
NFL Preseason (6 Matches)
12:30 AM
24/08/25
4389
San Francisco 49ers
30
4429
Los Angeles Chargers
23
W
08:00 PM
16/08/25
4390
Las Vegas Raiders
19
4389
San Francisco 49ers
22
W
12:30 AM
10/08/25
4389
San Francisco 49ers
9
4418
Denver Broncos
30
L
02:00 AM
24/08/24
4390
Las Vegas Raiders
24
4389
San Francisco 49ers
24
D
12:00 AM
19/08/24
4389
San Francisco 49ers
16
4425
New Orleans Saints
10
W
11:00 PM
10/08/24
4431
Tennessee Titans
17
4389
San Francisco 49ers
13
L

Jacksonville Jaguars Recent Matches

9464
NFL (24 Matches)
05:00 PM
21/09/25
4386
Jacksonville Jaguars
17
4324
Houston Texans
10
W
05:00 PM
14/09/25
4416
Cincinnati Bengals
31
4386
Jacksonville Jaguars
27
L
05:00 PM
07/09/25
4386
Jacksonville Jaguars
26
4415
Carolina Panthers
10
W
06:00 PM
05/01/25
4421
Indianapolis Colts
26
4386
Jacksonville Jaguars
23
L
06:00 PM
29/12/24
4386
Jacksonville Jaguars
20
4431
Tennessee Titans
13
W
09:25 PM
22/12/24
4390
Las Vegas Raiders
19
4386
Jacksonville Jaguars
14
L
06:00 PM
15/12/24
4386
Jacksonville Jaguars
25
4427
New York Jets
32
L
06:00 PM
08/12/24
4431
Tennessee Titans
6
4386
Jacksonville Jaguars
10
W
06:00 PM
01/12/24
4386
Jacksonville Jaguars
20
4324
Houston Texans
23
L
06:00 PM
17/11/24
4419
Detroit Lions
52
4386
Jacksonville Jaguars
6
L
06:00 PM
10/11/24
4386
Jacksonville Jaguars
7
4423
Minnesota Vikings
12
L
09:05 PM
03/11/24
4428
Philadelphia Eagles
28
4386
Jacksonville Jaguars
23
L
05:00 PM
27/10/24
4386
Jacksonville Jaguars
27
4420
Green Bay Packers
30
L
01:30 PM
20/10/24
4386
Jacksonville Jaguars
32
4424
New England Patriots
16
W
01:30 PM
13/10/24
4391
Chicago Bears
35
4386
Jacksonville Jaguars
16
L
05:00 PM
06/10/24
4386
Jacksonville Jaguars
37
4421
Indianapolis Colts
34
W
05:00 PM
29/09/24
4324
Houston Texans
24
4386
Jacksonville Jaguars
20
L
11:30 PM
23/09/24
4414
Buffalo Bills
47
4386
Jacksonville Jaguars
10
L
05:00 PM
15/09/24
4386
Jacksonville Jaguars
13
4417
Cleveland Browns
18
L
05:00 PM
08/09/24
4287
Miami Dolphins
20
4386
Jacksonville Jaguars
17
L
06:00 PM
07/01/24
4431
Tennessee Titans
28
4386
Jacksonville Jaguars
20
L
06:00 PM
31/12/23
4386
Jacksonville Jaguars
26
4415
Carolina Panthers
0
W
09:05 PM
24/12/23
4388
Tampa Bay Buccaneers
30
4386
Jacksonville Jaguars
12
L
01:20 AM
18/12/23
4386
Jacksonville Jaguars
7
4413
Baltimore Ravens
23
L
9465
NFL Preseason (6 Matches)
11:00 PM
23/08/25
4287
Miami Dolphins
14
4386
Jacksonville Jaguars
6
L
05:00 PM
17/08/25
4425
New Orleans Saints
17
4386
Jacksonville Jaguars
17
D
11:00 PM
09/08/25
4386
Jacksonville Jaguars
25
4345
Pittsburgh Steelers
31
L
11:00 PM
23/08/24
4393
Atlanta Falcons
0
4386
Jacksonville Jaguars
31
W
11:30 PM
17/08/24
4386
Jacksonville Jaguars
20
4388
Tampa Bay Buccaneers
7
W
11:00 PM
10/08/24
4386
Jacksonville Jaguars
26
4422
Kansas City Chiefs
13
W

San Francisco 49ers Next Fixtures

9464
NFL
08:05 PM
28/09/25
4389
San Francisco 49ers
4386
Jacksonville Jaguars
Prediction
12:15 AM
03/10/25
4387
Los Angeles Rams
4389
San Francisco 49ers
Prediction
05:00 PM
12/10/25
4388
Tampa Bay Buccaneers
4389
San Francisco 49ers
Prediction
12:20 AM
20/10/25
4389
San Francisco 49ers
4393
Atlanta Falcons
Prediction
05:00 PM
26/10/25
4324
Houston Texans
4389
San Francisco 49ers
Prediction
06:00 PM
02/11/25
4426
New York Giants
4389
San Francisco 49ers
Prediction
09:25 PM
09/11/25
4389
San Francisco 49ers
4387
Los Angeles Rams
Prediction
09:05 PM
16/11/25
4412
Arizona Cardinals
4389
San Francisco 49ers
Prediction
01:15 AM
25/11/25
4389
San Francisco 49ers
4415
Carolina Panthers
Prediction
06:00 PM
30/11/25
4417
Cleveland Browns
4389
San Francisco 49ers
Prediction
09:25 PM
14/12/25
4389
San Francisco 49ers
4431
Tennessee Titans
Prediction
01:15 AM
23/12/25
4421
Indianapolis Colts
4389
San Francisco 49ers
Prediction
01:20 AM
29/12/25
4389
San Francisco 49ers
4391
Chicago Bears
Prediction
06:00 PM
04/01/26
4389
San Francisco 49ers
4430
Seattle Seahawks
Prediction

Jacksonville Jaguars Next Fixtures

9464
NFL
08:05 PM
28/09/25
4389
San Francisco 49ers
4386
Jacksonville Jaguars
Prediction
12:15 AM
07/10/25
4386
Jacksonville Jaguars
4422
Kansas City Chiefs
Prediction
05:00 PM
12/10/25
4386
Jacksonville Jaguars
4430
Seattle Seahawks
Prediction
01:30 PM
19/10/25
4386
Jacksonville Jaguars
4387
Los Angeles Rams
Prediction
09:05 PM
02/11/25
4390
Las Vegas Raiders
4386
Jacksonville Jaguars
Prediction
06:00 PM
09/11/25
4324
Houston Texans
4386
Jacksonville Jaguars
Prediction
06:00 PM
16/11/25
4386
Jacksonville Jaguars
4429
Los Angeles Chargers
Prediction
09:05 PM
23/11/25
4412
Arizona Cardinals
4386
Jacksonville Jaguars
Prediction
06:00 PM
30/11/25
4431
Tennessee Titans
4386
Jacksonville Jaguars
Prediction
06:00 PM
07/12/25
4386
Jacksonville Jaguars
4421
Indianapolis Colts
Prediction
06:00 PM
14/12/25
4386
Jacksonville Jaguars
4427
New York Jets
Prediction
09:05 PM
21/12/25
4418
Denver Broncos
4386
Jacksonville Jaguars
Prediction
06:00 PM
28/12/25
4421
Indianapolis Colts
4386
Jacksonville Jaguars
Prediction
06:00 PM
04/01/26
4386
Jacksonville Jaguars
4431
Tennessee Titans
Prediction

San Francisco 49ers Last Match Played stats

San Francisco 49ers vs Arizona Cardinals

Final Score :16 - 15

(H)Offense (A)
1Touchdowns1
3/3Field goals2/3
355Total yards260
1Turnovers0
1/4Red zone efficiency1/3
25:21Time of Possession34:39
19First downs16
1First downs by penalty1
2/10 (20%)Third down efficiency5/15 (33%)
3Punts5
42.7Average yards per punt51.6
5.7Average yards per play4.1
(H)Passing (A)
14First downs by passing8
282Net yards passing154
284Gross yards passing159
1Passing touchdowns1
1Interceptions thrown0
6.7Average passing yards per attempt4.3
4Red zone passing attempts3
(H)Rushing (A)
20Rushing attempts28
73Rushing yards106
3.7Average rushing yards per attempt3.8
4First downs by rushing7
6Red zone rushing attempts2
(H)Other (A)
5Penalties5
69Yards penalized30
0Fumbles1
0Fumbles lost0

Jacksonville Jaguars Last Match Played stats

Jacksonville Jaguars vs Houston Texans

Final Score :17 - 10

(H)Offense (A)
2Touchdowns1
1/2Field goals1/2
291Total yards271
1Turnovers3
2/3Red zone efficiency0/1
31:18Time of Possession28:42
17First downs13
3First downs by penalty2
4/15 (26%)Third down efficiency4/15 (26%)
6Punts6
48.8Average yards per punt43.5
4.4Average yards per play4.6
(H)Passing (A)
10First downs by passing8
205Net yards passing184
222Gross yards passing204
0Passing touchdowns1
1Interceptions thrown2
4.9Average passing yards per attempt4.6
2Red zone passing attempts2
(H)Rushing (A)
24Rushing attempts19
86Rushing yards87
3.6Average rushing yards per attempt4.6
5First downs by rushing2
3Red zone rushing attempts1
(H)Other (A)
9Penalties7
70Yards penalized66
0Fumbles1
0Fumbles lost1

NFL 25/26 Standings

POSTEAMMPWLPTS
1Philadelphia EaglesPhiladelphia Eagles3301
2San Francisco 49ersSan Francisco 49ers3301
3Los Angeles ChargersLos Angeles Chargers3301
4Indianapolis ColtsIndianapolis Colts3301
5Buffalo BillsBuffalo Bills3301
6Tampa Bay BuccaneersTampa Bay Buccaneers3301
7Green Bay PackersGreen Bay Packers3210.667
8Minnesota VikingsMinnesota Vikings3210.667
9Cincinnati BengalsCincinnati Bengals3210.667
10Detroit LionsDetroit Lions3210.667
11Seattle SeahawksSeattle Seahawks3210.667
12Washington CommandersWashington Commanders3210.667
13Pittsburgh SteelersPittsburgh Steelers3210.667
14Jacksonville JaguarsJacksonville Jaguars3210.667
15Arizona CardinalsArizona Cardinals3210.667
16Los Angeles RamsLos Angeles Rams3210.667
17Cleveland BrownsCleveland Browns3120.333
18Atlanta FalconsAtlanta Falcons3120.333
19Baltimore RavensBaltimore Ravens3120.333
20Chicago BearsChicago Bears3120.333
21Carolina PanthersCarolina Panthers3120.333
22Las Vegas RaidersLas Vegas Raiders3120.333
23Dallas CowboysDallas Cowboys3120.333
24Denver BroncosDenver Broncos3120.333
25Kansas City ChiefsKansas City Chiefs3120.333
26New England PatriotsNew England Patriots3120.333
27New York JetsNew York Jets3030
28Miami DolphinsMiami Dolphins3030
29New York GiantsNew York Giants3030
30Tennessee TitansTennessee Titans3030
31New Orleans SaintsNew Orleans Saints3030
32Houston TexansHouston Texans3030