San Francisco 49ers vs Carolina Panthers: Prediction, Head-to-Head, Odds & Stats (Tue, 25 Nov '25)
Wojtek Kolan
Published on 25 Nov, 01:15 AM UTC
Next Match 25/11/25 at 01:15 AM
San Francisco 49ers vs Carolina Panthers
📍 Levi's Stadium, USA.
Scheduled H2H Match For San Francisco 49ers Vs Carolina Panthers
NFL
Tue, 25 Nov 2025 at 01:15 AM UTC
San Francisco 49ers
USA
Recent Form
W
W
W
W
W
4
Win
Played
10
0 Draws6
Win
2
Position
21
Kyle Shanahan
Manager
Dave Canales
Carolina Panthers
USA
Recent Form
W
L
L
L
L
4
Win
Played
10
0 Draws6
Win
2
Position
21
Kyle Shanahan
Manager
Dave Canales
Game Schedule - Time Of Fixture
San Francisco 49ers will square off vs Carolina Panthers in NFL on Tue, 25 Nov 2025 at 01:15 AM UTC. Let’s investigate historical performances, recent stats and head-2-head information to find out the most accurate picks and best bets.
San Francisco 49ers vs Carolina Panthers H2H Game Summary
For the last 10 H2H games for these teams, San Francisco 49ers have come out on top 4 times and Carolina Panthers have won on 6 occasion. In the latest match between them, San Francisco 49ers won 15-37.
| Head-to-Head | Match Wins |
|---|---|
| San Francisco 49ers | 4 |
| Carolina Panthers | 6 |
San Francisco 49ers vs Carolina Panthers Past H2H Matches
NFL
08:05 PM
09/10/22
09/10/22
Carolina Panthers
15
San Francisco 49ers
37
08:05 PM
27/10/19
27/10/19
San Francisco 49ers
51
Carolina Panthers
13
08:25 PM
10/09/17
10/09/17
San Francisco 49ers
3
Carolina Panthers
23
05:00 PM
18/09/16
18/09/16
Carolina Panthers
46
San Francisco 49ers
27
06:05 PM
12/01/14
12/01/14
Carolina Panthers
10
San Francisco 49ers
23
09:05 PM
10/11/13
10/11/13
San Francisco 49ers
9
Carolina Panthers
10
05:00 PM
24/10/10
24/10/10
Carolina Panthers
23
San Francisco 49ers
20
06:00 PM
02/12/07
02/12/07
Carolina Panthers
31
San Francisco 49ers
14
09:15 PM
14/11/04
14/11/04
San Francisco 49ers
27
Carolina Panthers
37
06:00 PM
18/11/01
18/11/01
Carolina Panthers
22
San Francisco 49ers
25
06:00 PM
08/10/01
08/10/01
San Francisco 49ers
24
Carolina Panthers
14
San Francisco 49ers Recent Matches
NFL (24 Matches)
08:25 PM
21/09/25
21/09/25
San Francisco 49ers
16
Arizona Cardinals
15
W
05:00 PM
14/09/25
14/09/25
New Orleans Saints
21
San Francisco 49ers
26
W
08:05 PM
07/09/25
07/09/25
Seattle Seahawks
13
San Francisco 49ers
17
W
09:25 PM
05/01/25
05/01/25
Arizona Cardinals
47
San Francisco 49ers
24
L
01:15 AM
31/12/24
31/12/24
San Francisco 49ers
34
Detroit Lions
40
L
09:25 PM
22/12/24
22/12/24
Miami Dolphins
29
San Francisco 49ers
17
L
01:15 AM
13/12/24
13/12/24
San Francisco 49ers
6
Los Angeles Rams
12
L
09:25 PM
08/12/24
08/12/24
San Francisco 49ers
38
Chicago Bears
13
W
01:20 AM
02/12/24
02/12/24
Buffalo Bills
35
San Francisco 49ers
10
L
09:25 PM
24/11/24
24/11/24
Green Bay Packers
38
San Francisco 49ers
10
L
09:05 PM
17/11/24
17/11/24
San Francisco 49ers
17
Seattle Seahawks
20
L
06:00 PM
10/11/24
10/11/24
Tampa Bay Buccaneers
20
San Francisco 49ers
23
W
12:20 AM
28/10/24
28/10/24
San Francisco 49ers
30
Dallas Cowboys
24
W
08:25 PM
20/10/24
20/10/24
San Francisco 49ers
18
Kansas City Chiefs
28
L
12:15 AM
11/10/24
11/10/24
Seattle Seahawks
24
San Francisco 49ers
36
W
08:05 PM
06/10/24
06/10/24
San Francisco 49ers
23
Arizona Cardinals
24
L
08:05 PM
29/09/24
29/09/24
San Francisco 49ers
30
New England Patriots
13
W
08:25 PM
22/09/24
22/09/24
Los Angeles Rams
27
San Francisco 49ers
24
L
05:00 PM
15/09/24
15/09/24
Minnesota Vikings
23
San Francisco 49ers
17
L
12:15 AM
10/09/24
10/09/24
San Francisco 49ers
32
New York Jets
19
W
11:30 PM
11/02/24
11/02/24
Kansas City Chiefs
25
San Francisco 49ers
22
L
11:30 PM
28/01/24
28/01/24
San Francisco 49ers
34
Detroit Lions
31
W
01:15 AM
21/01/24
21/01/24
San Francisco 49ers
24
Green Bay Packers
21
W
09:25 PM
07/01/24
07/01/24
San Francisco 49ers
20
Los Angeles Rams
21
L
NFL Preseason (6 Matches)
12:30 AM
24/08/25
24/08/25
San Francisco 49ers
30
Los Angeles Chargers
23
W
08:00 PM
16/08/25
16/08/25
Las Vegas Raiders
19
San Francisco 49ers
22
W
12:30 AM
10/08/25
10/08/25
San Francisco 49ers
9
Denver Broncos
30
L
02:00 AM
24/08/24
24/08/24
Las Vegas Raiders
24
San Francisco 49ers
24
D
12:00 AM
19/08/24
19/08/24
San Francisco 49ers
16
New Orleans Saints
10
W
11:00 PM
10/08/24
10/08/24
Tennessee Titans
17
San Francisco 49ers
13
L
Carolina Panthers Recent Matches
NFL (24 Matches)
05:00 PM
21/09/25
21/09/25
Carolina Panthers
30
Atlanta Falcons
0
W
08:05 PM
14/09/25
14/09/25
Arizona Cardinals
27
Carolina Panthers
22
L
05:00 PM
07/09/25
07/09/25
Jacksonville Jaguars
26
Carolina Panthers
10
L
06:00 PM
05/01/25
05/01/25
Atlanta Falcons
38
Carolina Panthers
44
W
06:00 PM
29/12/24
29/12/24
Tampa Bay Buccaneers
48
Carolina Panthers
14
L
06:00 PM
22/12/24
22/12/24
Carolina Panthers
36
Arizona Cardinals
30
W
06:00 PM
15/12/24
15/12/24
Carolina Panthers
14
Dallas Cowboys
30
L
06:00 PM
08/12/24
08/12/24
Philadelphia Eagles
22
Carolina Panthers
16
L
09:05 PM
01/12/24
01/12/24
Carolina Panthers
23
Tampa Bay Buccaneers
26
L
06:00 PM
24/11/24
24/11/24
Carolina Panthers
27
Kansas City Chiefs
30
L
02:30 PM
10/11/24
10/11/24
Carolina Panthers
20
New York Giants
17
W
06:00 PM
03/11/24
03/11/24
Carolina Panthers
23
New Orleans Saints
22
W
08:25 PM
27/10/24
27/10/24
Denver Broncos
28
Carolina Panthers
14
L
08:05 PM
20/10/24
20/10/24
Washington Commanders
40
Carolina Panthers
7
L
08:25 PM
13/10/24
13/10/24
Carolina Panthers
20
Atlanta Falcons
38
L
05:00 PM
06/10/24
06/10/24
Chicago Bears
36
Carolina Panthers
10
L
05:00 PM
29/09/24
29/09/24
Carolina Panthers
24
Cincinnati Bengals
34
L
08:05 PM
22/09/24
22/09/24
Las Vegas Raiders
22
Carolina Panthers
36
W
05:00 PM
15/09/24
15/09/24
Carolina Panthers
3
Los Angeles Chargers
26
L
05:00 PM
08/09/24
08/09/24
New Orleans Saints
47
Carolina Panthers
10
L
06:00 PM
07/01/24
07/01/24
Carolina Panthers
0
Tampa Bay Buccaneers
9
L
06:00 PM
31/12/23
31/12/23
Jacksonville Jaguars
26
Carolina Panthers
0
L
06:00 PM
24/12/23
24/12/23
Carolina Panthers
30
Green Bay Packers
33
L
06:00 PM
17/12/23
17/12/23
Carolina Panthers
9
Atlanta Falcons
7
W
NFL Preseason (6 Matches)
11:00 PM
21/08/25
21/08/25
Carolina Panthers
10
Pittsburgh Steelers
19
L
05:00 PM
16/08/25
16/08/25
Houston Texans
20
Carolina Panthers
3
L
11:00 PM
08/08/25
08/08/25
Carolina Panthers
10
Cleveland Browns
30
L
05:00 PM
24/08/24
24/08/24
Buffalo Bills
26
Carolina Panthers
31
W
11:00 PM
17/08/24
17/08/24
Carolina Panthers
12
New York Jets
15
L
11:00 PM
08/08/24
08/08/24
New England Patriots
17
Carolina Panthers
3
L
San Francisco 49ers Next Fixtures
NFL
08:05 PM
28/09/25
28/09/25
San Francisco 49ers
Jacksonville Jaguars
Prediction
12:15 AM
03/10/25
03/10/25
Los Angeles Rams
San Francisco 49ers
Prediction
05:00 PM
12/10/25
12/10/25
Tampa Bay Buccaneers
San Francisco 49ers
Prediction
12:20 AM
20/10/25
20/10/25
San Francisco 49ers
Atlanta Falcons
Prediction
05:00 PM
26/10/25
26/10/25
Houston Texans
San Francisco 49ers
Prediction
06:00 PM
02/11/25
02/11/25
New York Giants
San Francisco 49ers
Prediction
09:25 PM
09/11/25
09/11/25
San Francisco 49ers
Los Angeles Rams
Prediction
09:05 PM
16/11/25
16/11/25
Arizona Cardinals
San Francisco 49ers
Prediction
01:15 AM
25/11/25
25/11/25
San Francisco 49ers
Carolina Panthers
Prediction
06:00 PM
30/11/25
30/11/25
Cleveland Browns
San Francisco 49ers
Prediction
09:25 PM
14/12/25
14/12/25
San Francisco 49ers
Tennessee Titans
Prediction
01:15 AM
23/12/25
23/12/25
Indianapolis Colts
San Francisco 49ers
Prediction
01:20 AM
29/12/25
29/12/25
San Francisco 49ers
Chicago Bears
Prediction
06:00 PM
04/01/26
04/01/26
San Francisco 49ers
Seattle Seahawks
Prediction
Carolina Panthers Next Fixtures
NFL
05:00 PM
28/09/25
28/09/25
New England Patriots
Carolina Panthers
Prediction
05:00 PM
05/10/25
05/10/25
Carolina Panthers
Miami Dolphins
Prediction
05:00 PM
12/10/25
12/10/25
Carolina Panthers
Dallas Cowboys
Prediction
05:00 PM
19/10/25
19/10/25
New York Jets
Carolina Panthers
Prediction
05:00 PM
26/10/25
26/10/25
Carolina Panthers
Buffalo Bills
Prediction
06:00 PM
02/11/25
02/11/25
Green Bay Packers
Carolina Panthers
Prediction
06:00 PM
09/11/25
09/11/25
Carolina Panthers
New Orleans Saints
Prediction
06:00 PM
16/11/25
16/11/25
Atlanta Falcons
Carolina Panthers
Prediction
01:15 AM
25/11/25
25/11/25
San Francisco 49ers
Carolina Panthers
Prediction
06:00 PM
30/11/25
30/11/25
Carolina Panthers
Los Angeles Rams
Prediction
09:25 PM
14/12/25
14/12/25
New Orleans Saints
Carolina Panthers
Prediction
06:00 PM
21/12/25
21/12/25
Carolina Panthers
Tampa Bay Buccaneers
Prediction
06:00 PM
28/12/25
28/12/25
Carolina Panthers
Seattle Seahawks
Prediction
06:00 PM
04/01/26
04/01/26
Tampa Bay Buccaneers
Carolina Panthers
Prediction
San Francisco 49ers Last Match Played stats
San Francisco 49ers vs Arizona Cardinals
Final Score :16 - 15
| (H) | Offense | (A) |
|---|---|---|
| 1 | Touchdowns | 1 |
| 3/3 | Field goals | 2/3 |
| 355 | Total yards | 260 |
| 1 | Turnovers | 0 |
| 1/4 | Red zone efficiency | 1/3 |
| 25:21 | Time of Possession | 34:39 |
| 19 | First downs | 16 |
| 1 | First downs by penalty | 1 |
| 2/10 (20%) | Third down efficiency | 5/15 (33%) |
| 3 | Punts | 5 |
| 42.7 | Average yards per punt | 51.6 |
| 5.7 | Average yards per play | 4.1 |
| (H) | Passing | (A) |
| 14 | First downs by passing | 8 |
| 282 | Net yards passing | 154 |
| 284 | Gross yards passing | 159 |
| 1 | Passing touchdowns | 1 |
| 1 | Interceptions thrown | 0 |
| 6.7 | Average passing yards per attempt | 4.3 |
| 4 | Red zone passing attempts | 3 |
| (H) | Rushing | (A) |
| 20 | Rushing attempts | 28 |
| 73 | Rushing yards | 106 |
| 3.7 | Average rushing yards per attempt | 3.8 |
| 4 | First downs by rushing | 7 |
| 6 | Red zone rushing attempts | 2 |
| (H) | Other | (A) |
| 5 | Penalties | 5 |
| 69 | Yards penalized | 30 |
| 0 | Fumbles | 1 |
| 0 | Fumbles lost | 0 |
Carolina Panthers Last Match Played stats
Carolina Panthers vs Atlanta Falcons
Final Score :30 - 0
| (H) | Offense | (A) |
|---|---|---|
| 3 | Touchdowns | 0 |
| 3/3 | Field goals | 0/2 |
| 224 | Total yards | 332 |
| 1 | Turnovers | 3 |
| 2/3 | Red zone efficiency | 0/0 |
| 31:58 | Time of Possession | 28:02 |
| 15 | First downs | 17 |
| 0 | First downs by penalty | 1 |
| 3/11 (27%) | Third down efficiency | 5/13 (38%) |
| 3 | Punts | 3 |
| 45 | Average yards per punt | 32 |
| 4.1 | Average yards per play | 5 |
| (H) | Passing | (A) |
| 7 | First downs by passing | 11 |
| 114 | Net yards passing | 201 |
| 121 | Gross yards passing | 201 |
| 0 | Passing touchdowns | 0 |
| 0 | Interceptions thrown | 2 |
| 4.6 | Average passing yards per attempt | 4.7 |
| 6 | Red zone passing attempts | 0 |
| (H) | Rushing | (A) |
| 30 | Rushing attempts | 23 |
| 110 | Rushing yards | 131 |
| 3.7 | Average rushing yards per attempt | 5.7 |
| 7 | First downs by rushing | 6 |
| 6 | Red zone rushing attempts | 0 |
| (H) | Other | (A) |
| 6 | Penalties | 3 |
| 55 | Yards penalized | 23 |
| 1 | Fumbles | 1 |
| 1 | Fumbles lost | 1 |
NFL 25/26 Standings
| POS | TEAM | MP | W | L | PTS |
|---|---|---|---|---|---|
| 1 |  Philadelphia Eagles | 3 | 3 | 0 | 1 |
| 2 |  San Francisco 49ers | 3 | 3 | 0 | 1 |
| 3 |  Los Angeles Chargers | 3 | 3 | 0 | 1 |
| 4 |  Indianapolis Colts | 3 | 3 | 0 | 1 |
| 5 |  Buffalo Bills | 3 | 3 | 0 | 1 |
| 6 |  Tampa Bay Buccaneers | 3 | 3 | 0 | 1 |
| 7 |  Green Bay Packers | 3 | 2 | 1 | 0.667 |
| 8 |  Minnesota Vikings | 3 | 2 | 1 | 0.667 |
| 9 |  Cincinnati Bengals | 3 | 2 | 1 | 0.667 |
| 10 |  Detroit Lions | 3 | 2 | 1 | 0.667 |
| 11 |  Seattle Seahawks | 3 | 2 | 1 | 0.667 |
| 12 |  Washington Commanders | 3 | 2 | 1 | 0.667 |
| 13 |  Pittsburgh Steelers | 3 | 2 | 1 | 0.667 |
| 14 |  Jacksonville Jaguars | 3 | 2 | 1 | 0.667 |
| 15 |  Arizona Cardinals | 3 | 2 | 1 | 0.667 |
| 16 |  Los Angeles Rams | 3 | 2 | 1 | 0.667 |
| 17 |  Cleveland Browns | 3 | 1 | 2 | 0.333 |
| 18 |  Atlanta Falcons | 3 | 1 | 2 | 0.333 |
| 19 |  Baltimore Ravens | 3 | 1 | 2 | 0.333 |
| 20 |  Chicago Bears | 3 | 1 | 2 | 0.333 |
| 21 |  Carolina Panthers | 3 | 1 | 2 | 0.333 |
| 22 |  Las Vegas Raiders | 3 | 1 | 2 | 0.333 |
| 23 |  Dallas Cowboys | 3 | 1 | 2 | 0.333 |
| 24 |  Denver Broncos | 3 | 1 | 2 | 0.333 |
| 25 |  Kansas City Chiefs | 3 | 1 | 2 | 0.333 |
| 26 |  New England Patriots | 3 | 1 | 2 | 0.333 |
| 27 |  New York Jets | 3 | 0 | 3 | 0 |
| 28 |  Miami Dolphins | 3 | 0 | 3 | 0 |
| 29 |  New York Giants | 3 | 0 | 3 | 0 |
| 30 |  Tennessee Titans | 3 | 0 | 3 | 0 |
| 31 |  New Orleans Saints | 3 | 0 | 3 | 0 |
| 32 |  Houston Texans | 3 | 0 | 3 | 0 |